2021

Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents.
Bošnjak B, Odak I, Barros-Martins J, Sandrock I, Hammerschmidt SI, Permanyer M, Patzer GE, Greorgiev H, Gutierrez Jauregui R, Tscherne A, Schwarz JH, Kalodimou G, Ssebyatika G, Ciurkiewicz M, Willenzon S, Bubke A, Ristenpart J, Ritter C, Tuchel T, Meyer Zu Natrup C, Shin DL, Clever S, Limpinsel L, Baumgärtner W, Krey T, Volz A, Sutter G, Förster R.
Front Immunol. 2021 Nov 11;12:772240. doi: 10.3389/fimmu.2021.772240. PMID: 34858430; PMCID: PMC8632543.

T. Assembly of infectious Kaposi's sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer.
Naniima P, Naimo E, Koch S, Curth U, Alkharsah KR, Ströh LJ, Binz A, Beneke JM, Vollmer B, Böning H, Borst EM, Desai P, Bohne J, Messerle M, Bauerfeind R, Legrand P, Sodeik B, Schulz TF, Krey T.
PLoS Biol. 2021 Nov 4;19(11):e3001423. doi: 10.1371/journal.pbio.3001423. PMID: 34735435; PMCID: PMC8568140.

Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies.
Bankwitz D, Bahai A, Labuhn M, Doepke M, Ginkel C, Khera T, Todt D, Ströh LJ, Dold L, Klein F, Klawonn F, Krey T, Behrendt P, Cornberg M, McHardy AC, Pietschmann T.
Gut. 2021 Sep;70(9):1734-1745. doi: 10.1136/gutjnl-2020-321190. Epub 2020 Dec 15. PMID: 33323394

Fixed-target serial femtosecond crystallography using in cellulo grown microcrystals.
Lahey-Rudolph JM, Schönherr R, Barthelmess M, Fischer P, Seuring C, Wagner A, Meents A, Redecke L.
IUCrJ. 2021 Jun 18;8(Pt 4):665-677. doi: 10.1107/S2052252521005297. eCollection 2021 Jul 1.

Recruitment of phospholipase Cγ1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation.
Samarina N, Ssebyatika G, Tikla T, Waldmann JY, Abere B, Nanna V, Marasco M, Carlomagno T, Krey T, Schulz TF.
PLoS Pathog. 2021 Jun 18;17(6):e1009635. doi: 10.1371/journal.ppat.1009635. Online ahead of print. PMID: 34143834

A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip.
Norton-Baker B, Mehrabi P, Boger J, Schönherr R, von Stetten D, Schikora H, Kwok AO, Martin RW, Miller RJD, Redecke L, Schulz EC.
Acta Crystallogr D Struct Biol. 2021 Jun 1;77(Pt 6):820-834. doi: 10.1107/S2059798321003855. Epub 2021 May 19. PMID: 34076595

Is LRP2 Involved in Leptin Transport over the Blood-Brain Barrier and Development of Obesity?
Sandin ES, Folberth J, Müller-Fielitz H, Pietrzik CU, Herold E, Willnow TE, Pfluger PT, Nogueiras R, Prevot V, Krey T, Schwaninger M.
Int J Mol Sci. 2021 May 8;22(9):4998. doi: 10.3390/ijms22094998. PMID: 34066779

Three LysM effectors of Zymoseptoria tritici collectively disarm chitin-triggered plant immunity.
Tian H, MacKenzie CI, Rodriguez-Moreno L, van den Berg GCM, Chen H, Rudd JJ, Mesters JR, Thomma BPHJ.
Mol Plant Pathol. 2021; 22, 683–693. doi: 10.1111/mpp.13055

The tetrameric structure of the novel haloalkane dehalogenase DpaA from Paraglaciecola agarilytica NO2.
Mazur A, Prudnikova T, Grinkevich P, Mesters JR, Mrazova D, Chaloupkova R, Damborsky J, Kuty M, Kolenko P, Kuta Smatanova I
The tetrameric structure of the novel haloalkane dehalogenase DpaA from Paraglaciecola agarilytica NO2.Acta Cryst. 2021; D77, 347-356. doi: 10.1107/S2059798321000486

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.
Koudelka T, Boger J, Henkel A, Schönherr R, Krantz S, Fuchs S, Rodríguez E, Redecke L, Tholey A.
Proteomics. 2021 Jan;21(2):e2000246. doi: 10.1002/pmic.202000246. Epub 2020 Nov 17. PMID: 33111431